Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity associated with bortezomib, a proteasome inhibitor used in the therapy of numerous myeloma. Its synthesis or study is crucial for guaranteeing the purity and basic safety from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound while in the synthesis of imatinib, a drug that targets unique different types of most cancers, such as Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their study is crucial for optimizing the creation system and making certain significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to take care of breast most cancers, and these intermediates are associated with its output.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the treatment Cb 7598 of breast most cancers. Various intermediates assist in the synthesis of the drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug helpful in managing cancers which include ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine chemotherapy drug used in the remedy of colorectal most cancers and little cell lung most cancers.
3-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound is linked to the synthesis of adamantane derivatives, which have a variety of purposes, like antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for sort two diabetic issues that inhibits the enzyme DPP-4 to regulate blood sugar degrees.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved with the synthesis of various gluconic acid derivatives, that are Employed in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor within the synthesis of canagliflozin, a medication utilized to handle kind two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).